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Through Kissei Pharmaceutical Co., Ltd, this randomized, phase III study investigate the efficacy, safety, and pharmacokinetics of R788 (also known as Fostamatinib) in adult patients with chronic immune thrombocytopenia. The goal of this study is also to investigate the safety and efficacy of long term dosing of R788 in patients with chronic idiopathic thrombocytopenic purpura. Participants are required to be over the age of 20 years, and have chronic ITP with platelet counts below 30K microliters. Participants must also have failed at least one ITP therapy previously.